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The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review

Leptin and ghrelin are two hormones that have been recognized to have a major
influence on energy balance. Leptin is a mediator of long-term regulation of energy
balance, suppressing food intake and thereby inducing weight loss. Ghrelin on
the other hand is a fast-acting hormone, seemingly playing a role in meal initiation.
As a growing number of people suffer from obesity, understanding the
mechanisms by which various hormones and neurotransmitters have influence on
energy balance has been a subject of intensive research.

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