What is the Tablet Version?
This tablet is the first tablet of its kind. It is brought to you by the same manufacturer of the weekly injection, Novo Nordisk. It has the same active ingredient as Ozempic - known as Semaglutide.
Although the medication is the exact same as the weekly jab, due to how our body processes oral tablets, it has been created as a daily tablet to ensure enough of the medication stays in your system.
How does it work?
The tablet works in three main ways. The medication mimics a natural hormone already found in your body (GLP-1).
It blocks a key hunger hormone telling your brain that you are hungry, whilst also helping to reduce leptin resistance (a hormone which can help off-set weight gain by increasing satiety aka fullness, and speed up your metabolism to help regulate the levels of fatty tissue in your body). This also helps stop the weight from coming straight back on when you stop the jab.
It slows down the gastric emptying process, meaning that your body takes longer to process food and it is fuller for longer. This means your body does not need as much intake as normal as it works off the food it has.
The medication helps to speed up your metabolism and increase fat burning by reducing glucogen & reducing insulin resistance. This promotes normal blood glucose levels, the liver metabolism of glucose and helps adipose tissue burn fat in a safe and controlled method without causing a sugar-crash. This avoids the urges for quick-fix sugary foods.
This all helps to reduce the risk of the so-called "starvation mode" and other side effects like ketoacidosis, as you will be burning off a mixture of stored carbs & fats.
Unlike fad diets which tend to starve the body when it's shouting out for food, the medication reduces your body's desire for food, which makes it easier to make healthier choices and to reduce calories. It also stops leptin levels from rising due to "starvation". Low leptin levels can cause increased hunger & a slower metabolism!
This means that when you stop using the medication, the body isn't desperate for sustenance and therefore, you won't suddenly begin storing fat and gain all the weight back.
How do I use it?
You must have a full consultation to look at your options first and to ensure your safety & suitability for medication. This particularly type comes as a daily tablet. Whilst it is the same medication as the weekly jab, it needs to be taken daily as our body acts much faster at metabolising oral medication than injections.
Where can I get it?
This is a prescription-only medication and must be prescribed by a qualified prescriber following a medical consultation. Your full medical history and circumstances will be taken into account to ensure safety & suitability.
Please note that this medication is not yet licensed for weight loss. Therefore it must be prescribed by a medically qualified clinician with weight management experience and as an option following other attempts to lose weight.
We prescribe and dispense only from within the UK following a full medical consultation - your safety is paramount.
What about side effects?
Like any new medication introduced to your body, your body will have to adjust to it. Side effects are generally mild and are transient - which means they will go after a few days once your body has adjusted. Side effects may include headaches, nausea, dry mouth or tiredness.
During the consultation we go through the side effects & how to deal with them. We also send you aftercare information on how to deal with any potential side effects along with the Patient Information Leaflet, which goes into greater detail.
How much weight can I expect to lose?
According to the manufacturer's clinical trials, the average weight loss has been calculated as between 10lbs and 16lbs. But please know that everyone is different, so your weight loss may be more or it could be less. It is best not to compare yourself to others losing weight - focus on yourself, your goals and your progress.
How many tablets will I need?
We assess further courses by looking at the following factors:
Your overall target weight;
How well you take to the medication;
Your dose; and
Your weight at the end of your course.
Who is suitable?
Our medically trained clinicians will assess you on an individual basis, taking into account:
Your medical history
Your current medication
Current diet & eating habits
Current exercise levels
Other methods you have already tried
The programme is NOT suitable for:
Under 18's or Over 75's
Ladies who are breastfeeding or pregnant or actively trying to get pregnant.
Anyone who has had pancreatitis or thyroid tumours
Anyone with a history or direct family history of MEN2
Type 1 diabetics or patients taking diabetic medication
Renal (kidney) or liver disease
Anyone with heart failure
It is also advisable that you have previously used Saxenda or Ozempic, having tolerated it well before moving on to Rybelsus, or that you have tried other weight loss techniques or are needle-phobic. Medication should be a last resort.